Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1766795 | 0.93 | P2RX1 (0.47) | P2RX1KMT2AMEN1KCNMA1L3MBTL1 | |
| SCHEMBL1767290 | 0.93 | P2RX1 (0.47) | P2RX1KMT2AMEN1KCNMA1RAB9A | |
| SCHEMBL29257321 | 0.89 | P2RX1 (0.47) | P2RX1KMT2AMEN1KCNMA1RAB9A | |
| SCHEMBL31175825 | 0.89 | KMT2A (0.47) | P2RX1KMT2AMEN1KCNMA1RAB9A | |
| SCHEMBL29615050 | 0.88 | P2RX1 (0.46) | P2RX1KMT2AMEN1KCNMA1RAB9A | |
| SCHEMBL1766569 | 0.88 | P2RX1 (0.46) | P2RX1KMT2AMEN1KCNMA1CYP2C9 | |
| SCHEMBL16155805 | 0.88 | P2RX1 (0.43) | P2RX1KMT2AMEN1KCNMA1RAB9A | |
| SCHEMBL29549704 | 0.88 | P2RX1 (0.46) | P2RX1KMT2AMEN1KCNMA1CYP2C9 | |
| SCHEMBL29695914 | 0.88 | P2RX1 (0.46) | P2RX1KMT2AMEN1KCNMA1CYP2C9 | |
| SCHEMBL1766786 | 0.88 | P2RX1 (0.46) | P2RX1KMT2AMEN1KCNMA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038691-B | Bisamide compound and application thereof | 广西思钺生物科技有限责任公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113149900-B | Amide compound and application thereof | 沈阳化工大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-112430210-B | Bisamide compound and application thereof | 沈阳化工大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-111793008-B | Meta-diamide compound and application thereof | 沈阳化工大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-112430211-B | Isophthalamide compound and application thereof | 沈阳化工大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114555559-B | Isophthalamide compound and application thereof | 广西思钺生物科技有限责任公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20230065544-A1 | ISOPHTHALAMINDE COMPOUND AND USE THEREOF | Metisa Biotechnology Co., Ltd (CN) | 2023-03-02 | — | — | US | disclosed |
| CN-115038691-A | Bisamide compound and application thereof | 广西思钺生物科技有限责任公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220220073-A1 | BISAMIDE COMPOUND AND APPLICATION THEREOF | Metisa Biotechnology Co., Ltd (CN) | 2022-07-14 | — | — | US | disclosed |
| CN-114555559-A | Isophthalamide compound and application thereof | 广西思钺生物科技有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-113149900-A | Amide compound and application thereof | 沈阳化工大学 | 2021-07-23 | — | — | CN | disclosed |
| WO-2021139370-A1 | AMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021036965-A1 | ISOPHTHALAMIDE COMPOUND AND USE THEREOF | 沈阳化工大学 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036966-A1 | BISAMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-03-04 | — | — | WO | disclosed |
| CN-112430210-A | Bisamide compound and application thereof | 沈阳化工大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-112430211-A | Isophthalamide compound and application thereof | 沈阳化工大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-111793008-A | Metadiamide compound and application thereof | 沈阳化工大学 | 2020-10-20 | — | — | CN | disclosed |
| WO-2020200290-A1 | META-DIAMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065544-A1 | ISOPHTHALAMINDE COMPOUND AND USE THEREOF | DDT, INMT, CYP2B6 | P2RX1 2468/4885KMT2A 431/4885MEN1 3673/4885 |
| US-20220220073-A1 | BISAMIDE COMPOUND AND APPLICATION THEREOF | FHIT, DDT, BCHE | P2RX1 1495/4885KMT2A 116/4885MEN1 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.