SCHEMBL1766569

SCHEMBL1766569

O=C(Nc1c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C(F)(F)F)c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 2/20 0.46
KCNMA1 Q12791 4/20 0.43
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
CYP2C9 P11712 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
DHODH Q02127 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
RORC P51449 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.38
CCR6 P51684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29695914 1.00 P2RX1 (0.46) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL29549704 1.00 P2RX1 (0.46) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL1766723 0.95 P2RX1 (0.44) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL1766795 0.93 P2RX1 (0.47) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL1766495 0.90 P2RX1 (0.44) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL12439877 0.89 P2RX1 (0.47) P2RX1KCNMA1LMNACYP2C9KMT2A
SCHEMBL29615050 0.88 P2RX1 (0.46) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL22497571 0.88 P2RX1 (0.43) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL1766786 0.88 P2RX1 (0.46) P2RX1KCNMA1MAPTLMNACYP2C9
SCHEMBL1766464 0.85 P2RX1 (0.42) P2RX1KCNMA1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3684181-B1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2025-10-22 EP disclosed
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-08-05 US disclosed
CN-114591192-B Preparation method of N-cyclopropylmethyl aniline compound 江西仰立新材料有限公司 2024-06-21 CN disclosed
CN-117466813-A Meta-aminobenzoic acid bisamide compound and intermediate thereof 湖南化工研究院有限公司 2024-01-30 CN disclosed
CN-116621727-A Aryl or heteroaryl substituted meta-diamide compound or salt acceptable as pesticide, composition and application thereof 海利尔药业集团股份有限公司 2023-08-22 CN disclosed
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-07-20 US disclosed
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS AGRO, INC. (JP) 2023-07-11 US disclosed
US-11407710-B2 Method for preparing an N-cyclopropylmethyl aniline compound Jiangxi Univate New Material Co., LTD. 2022-08-09 US disclosed
US-20220177414-A1 METHOD FOR PREPARING AN N-CYCLOPROPYLMETHYL ANILINE COMPOUND Jiangxi Univate New Material Co., LTD. (CN) 2022-06-09 US disclosed
CN-114591192-A Preparation method of N-cyclopropylmethylaniline compound 江西仰立新材料有限公司 2022-06-07 CN disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
CN-102119143-A Amide derivative, pest control agent containing the same, and method of using the pest control agent MITSUI CHEMICALS AGRO INC 2011-07-06 CN disclosed
CN-102112437-A Amide derivative, pest control agent containing same, and pest control method MITSUI CHEMICALS AGRO INC 2011-06-29 CN disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT P2RX1 873/4885KCNMA1 691/4885MAPT 3034/4885
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 P2RX1 4192/4885KCNMA1 844/4885MAPT 4155/4885
US-11407710-B2 Method for preparing an N-cyclopropylmethyl aniline compound PPOX, HAAO, DAO P2RX1 1310/4885KCNMA1 3856/4885MAPT 3772/4885
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MTX1, ENPP1, CAT P2RX1 873/4885KCNMA1 691/4885MAPT 3034/4885
US-20220177414-A1 METHOD FOR PREPARING AN N-CYCLOPROPYLMETHYL ANILINE COMPOUND PPOX, HAAO, DAO P2RX1 1310/4885KCNMA1 3856/4885MAPT 3772/4885
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT P2RX1 873/4885KCNMA1 691/4885MAPT 3034/4885
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 P2RX1 3026/4885KCNMA1 904/4885MAPT 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.