Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196893 | 1.00 | ABCB1 (0.39) | ABCB1MAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL12293879 | 0.95 | ABCB1 (0.42) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL64690 | 0.95 | ABCB1 (0.42) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL20841754 | 0.95 | CTSV (0.37) | MAPTSMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL954434 | 0.94 | ABCB1 (0.41) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL2680751 | 0.93 | ABCB1 (0.40) | ABCB1MAPTCDC7ALDH1A1ADORA3 | |
| SCHEMBL20841761 | 0.92 | ABCB1 (0.39) | ABCB1SMN1; SMN2NPC1RAB9ACDC7 | |
| SCHEMBL10196888 | 0.92 | ABCB1 (0.39) | ABCB1SMN1; SMN2NPC1RAB9ACDC7 | |
| SCHEMBL20841729 | 0.90 | ABCB1 (0.38) | ABCB1SMN1; SMN2CDC7ALDH1A1ADORA3 | |
| SCHEMBL10196941 | 0.90 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239884-B2 | Coelenterazine compounds and uses thereof | KEIO UNIVERSITY (JP) | 2019-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239884-B2 | Coelenterazine compounds and uses thereof | CTRC, GLB1, GALC | ABCB1 1817/4885MAPT 4109/4885SMN1; SMN2 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.