Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388637 | 0.96 | ADORA2A (0.49) | ADORA2AADORA1GCKTGFBR1PTGS1 | |
| SCHEMBL9342675 | 0.86 | KMT2A (0.50) | ADORA2AADORA1TGFBR1MAP4K4ALDH1A1 | |
| SCHEMBL6545410 | 0.85 | ADORA2A (0.50) | ADORA2AADORA1GCKTGFBR1MAP4K4 | |
| SCHEMBL9343291 | 0.85 | TGFBR1 (0.44) | ADORA2AADORA1TGFBR1MAP4K4ALDH1A1 | |
| SCHEMBL4796319 | 0.83 | TGFBR1 (0.43) | ADORA2AADORA1GCKTGFBR1MAP4K4 | |
| SCHEMBL9764726 | 0.83 | PTGS1 (0.46) | ADORA2AADORA1GCKTGFBR1PTGS1 | |
| SCHEMBL4796326 | 0.83 | MEN1 (0.56) | ADORA2AADORA1GCKTGFBR1MAP4K4 | |
| SCHEMBL9340516 | 0.83 | NR1I2 (0.46) | ADORA2AADORA1TGFBR1PTGS1PTGS2 | |
| SCHEMBL1476228 | 0.81 | RXRA (0.49) | — | |
| SCHEMBL12301193 | 0.79 | MAPT (0.61) | TDP1ALDH1A1L3MBTL1CHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| EP-2220083-B1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | JANSSEN PHARMACEUTICALS INC (US) | 2017-07-19 | — | — | EP | disclosed |
| US-7863293-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| EP-2170065-A1 | DIPHENYL SUBSTITUTED ALKANES | Merck Sharp & Dohme Corp. (US) | 2010-04-07 | — | — | EP | disclosed |
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| US-7488728-B2 | Pyridinylmorpholine derivatives | ELI LILLY AND COMPANY (US) | 2009-02-10 | — | — | US | disclosed |
| WO-2008156721-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK & CO., INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED CORPORATION (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| US-4776880-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| CN-87103544-A | Fungicidal agents | ICI PLC (GB) | 1988-04-06 | — | — | CN | disclosed |
| US-4731107-A | Certain 6-diphenoxymethyl-2-pyridinyl-oxy-propanoates having herbicidal properties | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0243012-A2 | Pyridyl-acrylic acid ester derivatives, process for their preparation and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-28 | — | — | EP | disclosed |
| US-4692183-A | BROADLEAF GRASSES | THE DOW CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4685953-A | PREEMERGENCE AND POST EMERGENCE HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-08-11 | — | — | US | disclosed |
| US-4661144-A | Certain 6-aminomethyl or monoalkylamino or dialkylamino or heterocyclicamino-2-diphenoxymethyl pyridines having herbicidal activity | THE DOW CHEMICAL COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4606757-A | Diphenoxymethylpyridines having herbicidal properties | THE DOW CHEMICAL COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4251662-A | INSECTICIDES, MITICIDES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4123347-A | HYDROGEN DONOR SOLVENT | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | CXCR4, CXCR1, CXCR3 | ADORA2A 58/4885ADORA1 53/4885GCK 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.