Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.59 |
| ▸ | CDK1 | P06493 | 2/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.59 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | CDC7 | O00311 | 4/20 | 0.57 |
| ▸ | CDK2 | P24941 | 3/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.57 |
| ▸ | PIM1 | P11309 | 3/20 | 0.57 |
| ▸ | PRKACA | P17612 | 3/20 | 0.57 |
| ▸ | GSK3B | P49841 | 3/20 | 0.57 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.54 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25787926 | 0.86 | TGFBR1 (0.52) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL20846050 | 0.82 | CDC7 (0.50) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL5618155 | 0.82 | TGFBR1 (0.71) | CDC7CDK2MAP4K4PIM1PRKACA | |
| SCHEMBL29598987 | 0.80 | AXL (0.55) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL423854 | 0.80 | AXL (0.55) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL20846059 | 0.80 | CCNB2 (0.43) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL857182 | 0.80 | TGFBR1 (0.57) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL10124925 | 0.79 | IGF1R (0.58) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL20839192 | 0.78 | CAMKK2 (0.45) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL20846153 | 0.78 | CDC7 (0.51) | CCNB2CDK1CCNB1CCNB3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057660-A1 | INDOLE AND AZAINDOLE COMPOUNDS WITH SUBSTITUTED 6-MEMBERED ARYL AND HETEROARYL RINGS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2019-03-28 | — | — | WO | disclosed |