Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.60 |
| ▸ | CDC7 | O00311 | 5/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.57 |
| ▸ | PRKACA | P17612 | 4/20 | 0.57 |
| ▸ | CDK2 | P24941 | 4/20 | 0.57 |
| ▸ | HIPK2 | Q9H2X6 | 4/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.57 |
| ▸ | PIM1 | P11309 | 3/20 | 0.57 |
| ▸ | GSK3B | P49841 | 3/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.57 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.56 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.56 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.54 |
| ▸ | CDK9 | P50750 | 4/20 | 0.54 |
| ▸ | CLK2 | P49760 | 4/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740263 | 0.91 | CAMKK2 (0.69) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL858985 | 0.88 | CAMKK2 (0.70) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL5618155 | 0.86 | TGFBR1 (0.71) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL18418494 | 0.81 | CDC7 (0.71) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL15397129 | 0.80 | IKBKE (0.78) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL20846162 | 0.80 | AXL (0.64) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL20846051 | 0.80 | RPS6KA5 (0.58) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL857148 | 0.80 | TGFBR1 (0.57) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL858410 | 0.80 | TGFBR1 (0.57) | CAMKK2CDC7MAP4K4CLK4PRKACA | |
| SCHEMBL857182 | 0.80 | TGFBR1 (0.57) | CAMKK2CDC7MAP4K4CLK4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057660-A1 | INDOLE AND AZAINDOLE COMPOUNDS WITH SUBSTITUTED 6-MEMBERED ARYL AND HETEROARYL RINGS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2019-03-28 | — | — | WO | disclosed |