SCHEMBL20846558

SCHEMBL20846558

c1ccc(-c2cc(-c3cccc(N4c5ccccc5C5(c6cc7ccccc7cc64)c4ccsc4-c4sccc45)c3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
GLA P06280 1/20 0.33
NTSR1 P30989 1/20 0.32
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20846646 0.96 MEN1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846642 0.94 MEN1 (0.37) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846647 0.93 DHFR (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846650 0.92 MEN1 (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846668 0.92 MEN1 (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846561 0.91 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846759 0.91 GRM5 (0.35) MAPTTDP1
SCHEMBL20846625 0.89 CASP3 (0.31) MEN1KMT2AALDH1A1KDM4E
SCHEMBL20846645 0.88 MEN1 (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20846653 0.87 HPGD (0.37) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472564-B2 Delayed fluorescence compound and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-11-12 US disclosed
US-20190093009-A1 DELAYED FLUORESCENCE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472564-B2 Delayed fluorescence compound and organic electroluminescent device using the same SLCO4C1, LEF1, SLCO2A1 MEN1 3186/4885KMT2A 2759/4885ALDH1A1 2768/4885
US-20190093009-A1 DELAYED FLUORESCENCE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SLCO4C1, LEF1, SLCO2A1 MEN1 3186/4885KMT2A 2759/4885ALDH1A1 2768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.