Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355952 | 0.91 | CA12 (0.39) | LMNATDP1KDM4ECA12CA1 | |
| SCHEMBL20669502 | 0.85 | TDP1 (0.39) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL7586491 | 0.85 | TDP1 (0.39) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL12443569 | 0.79 | TDP1 (0.43) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL25590146 | 0.79 | TDP1 (0.43) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL25590147 | 0.79 | TDP1 (0.43) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL24085943 | 0.77 | LMNA (0.41) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL16029613 | 0.76 | LMNA (0.40) | LMNATDP1CNR1ADRA1AKDM4E | |
| SCHEMBL6435427 | 0.75 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL6435420 | 0.75 | RIPK1 (0.31) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658928-B1 | SURFACE-MODIFIED PIGMENT PREPARATIONS | BASF SE (DE) | 2019-03-27 | — | — | EP | disclosed |