Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669502 | 1.00 | TDP1 (0.39) | TDP1LMNACNR1ADRA1AKDM4E | |
| SCHEMBL6435427 | 0.90 | RIPK1 (0.31) | RIPK1ASAH1 | |
| SCHEMBL6435420 | 0.90 | RIPK1 (0.31) | RIPK1ASAH1 | |
| SCHEMBL1025269 | 0.85 | CA12 (0.32) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL1025270 | 0.85 | CA12 (0.32) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL20846641 | 0.85 | LMNA (0.36) | TDP1LMNACNR1ADRA1AKDM4E | |
| SCHEMBL6682980 | 0.83 | VDR (0.32) | — | |
| SCHEMBL12443569 | 0.82 | TDP1 (0.43) | TDP1LMNACNR1ADRA1AKDM4E | |
| SCHEMBL25590146 | 0.82 | TDP1 (0.43) | TDP1LMNACNR1ADRA1AKDM4E | |
| SCHEMBL25590147 | 0.82 | TDP1 (0.43) | TDP1LMNACNR1ADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692200-B1 | PROCESS FOR THE PREPARATION OF AMPHIPHILIC POLY (N-VINYL-2-PYRROLIDONE) BLOCK COPOLYMERS | LABOPHARM INC (CA) | 2012-09-19 | — | — | EP | claimed |
| US-20190048117-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE (US) | 2019-02-14 | — | — | US | disclosed |
| US-20140235782-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235782-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-8748548-B2 | Macromonomer mixture, terminal-reactive polymer mixture, intermediate for macromonomer and silicone hydrogel | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748548-B2 | Macromonomer mixture, terminal-reactive polymer mixture, intermediate for macromonomer and silicone hydrogel | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| WO-2011090683-A2 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| US-20110160385-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. | 2011-06-30 | — | — | US | disclosed |
| US-20110160385-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. | 2011-06-30 | — | — | US | disclosed |
| US-7375174-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375174-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2008-05-20 | — | — | US | disclosed |
| US-7250480-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2007-07-31 | — | — | US | disclosed |
| US-7250480-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2007-07-31 | — | — | US | disclosed |
| US-7220811-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220811-B2 | Acrylic composition and a curable coating composition including the same | BASF CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |
| EP-0957114-B1 | Azoamide compounds and their use as polymerisation initiators | WAKO PURE CHEM IND LTD (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6031084-A | Azoamide compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| JP-2000034265-A | NEW AZOAMIDE COMPOUND | WAKO PURE CHEM IND LTD | 2000-02-02 | — | — | JP | disclosed |
| EP-0957114-A1 | Azoamide compounds and their use as polymerisation initiators | Wako Pure Chemical Industries, Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |