Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 7/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847696 | 0.83 | MAPT (0.50) | MELKMAPTALDH1A1KDM4EGAA | |
| SCHEMBL22388781 | 0.80 | MELK (0.58) | MELKADRA2CMAPTALDH1A1KDM4E | |
| SCHEMBL7028384 | 0.78 | MAPT (0.47) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL29833278 | 0.78 | MAPT (0.64) | MELKADRA2CMAPTALDH1A1KDM4E | |
| SCHEMBL20847630 | 0.77 | DRD4 (0.69) | DRD2DRD4DRD3 | |
| SCHEMBL81814 | 0.76 | MAPT (0.65) | ADRA2CMAPTALDH1A1KDM4EGAA | |
| SCHEMBL15489560 | 0.76 | MAPT (0.65) | ADRA2CMAPTALDH1A1KDM4EGAA | |
| SCHEMBL20847624 | 0.74 | GPR119 (0.56) | MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16491157 | 0.73 | ALDH1A1 (0.49) | MELKADRA2CMAPTALDH1A1KDM4E | |
| SCHEMBL12349894 | 0.73 | GRM4 (0.43) | MAPTALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |