Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847627 | 0.85 | MAPT (0.55) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL20847625 | 0.83 | MELK (0.62) | MAPTALDH1A1KMT2AKDM4EMELK | |
| SCHEMBL22466092 | 0.80 | AKR1C3 (0.46) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL20273894 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL22388784 | 0.80 | MAPT (0.46) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL7028384 | 0.78 | MAPT (0.47) | MAPTALDH1A1HTTKMT2AMAPK1 | |
| SCHEMBL29833008 | 0.78 | PIK3CA (0.44) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL82183 | 0.76 | MAPT (0.67) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL24409249 | 0.75 | RAB9A (0.39) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL19078790 | 0.74 | AKR1C3 (0.62) | MAPTGAALMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |