SCHEMBL20847652

SCHEMBL20847652

CCOc1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
MAPT P10636 1/20 0.66
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
LTA4H P09960 1/20 0.57
ALDH1A1 P00352 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
GAA P10253 3/20 0.56
NPSR1 Q6W5P4 2/20 0.56
MAPK1 P28482 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
SQSTM1 Q13501 1/20 0.55
KEAP1 Q14145 1/20 0.55
NFE2L2 Q16236 1/20 0.55
NQO1 P15559 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931421 0.92 CA12 (0.70) MEN1KMT2AMAPTCA12CA1
SCHEMBL14707037 0.85 PKM (0.73) MEN1KMT2AMAPTCA12CA1
SCHEMBL10034484 0.85 GAA (0.61) MEN1KMT2AMAPTCA12CA1
SCHEMBL19339575 0.85 PKM (0.73) MEN1KMT2AMAPTCA12CA1
SCHEMBL18350017 0.84 CA12 (0.56) MEN1KMT2AMAPTCA12CA1
SCHEMBL17167776 0.83 CA2 (0.59) MEN1KMT2AMAPTCA12CA1
SCHEMBL417833 0.83 GAA (0.65) MEN1KMT2AMAPTCA12CA1
SCHEMBL11118343 0.83 TSHR (0.70) MEN1KMT2AMAPTCA12CA1
SCHEMBL18636141 0.82 LTA4H (0.59) MEN1KMT2AMAPTCA12CA1
SCHEMBL930465 0.81 RXFP1 (0.57) MEN1KMT2AMAPTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190097265-A1 PHASE-CHANGE NANOPARTICLES FOR LI-ION BATTERY SAFETY UNIVERSITY OF SOUTH FLORIDA (US) 2019-03-28 US disclosed