Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685881 | 1.00 | SIGMAR1 (0.68) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL5685898 | 1.00 | SIGMAR1 (0.68) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL11132051 | 0.89 | SIGMAR1 (0.64) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL15131040 | 0.89 | MEN1 (0.67) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL11133875 | 0.88 | SIGMAR1 (0.62) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL9774929 | 0.86 | ALDH1A1 (0.58) | SIGMAR1CYP1A2CYP2C19CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL9817426 | 0.85 | ALDH1A1 (0.56) | SIGMAR1CYP1A2CYP2C19CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL10564221 | 0.83 | KMT2A (0.54) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL14442995 | 0.82 | CYP1A2 (0.55) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 | |
| SCHEMBL13996935 | 0.82 | CYP1A2 (0.55) | SIGMAR1KCNH2ADRA1ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019058290-A1 | IMPROVED PROCESS FOR THE PREPARATION OF OZANIMOD Α-AMINO COMPOUND | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |