Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14442996 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL13996935 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| Benzylamine SCHEMBL5950282 | 0.84 | MAOA (0.47) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL20847996 | 0.82 | SIGMAR1 (0.68) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL5685898 | 0.82 | SIGMAR1 (0.68) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL5685881 | 0.82 | SIGMAR1 (0.68) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL10526089 | 0.81 | ADRA1A (0.57) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL10523532 | 0.81 | ADRA1A (0.57) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL13981594 | 0.81 | ALDH1A1 (0.56) | CYP1A2CYP2C19ADRA1AOPRK1TSHR | |
| SCHEMBL178505 | 0.81 | TAAR1 (0.63) | CYP1A2CYP2C19OPRK1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | CNR1, CNR2, GPR119 | CYP1A2 1463/4885CYP2C19 902/4885ADRA1A 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.