Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 8/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839012 | 0.80 | PIM1 (0.37) | ATRKCNH2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL29911105 | 0.80 | PIM1 (0.37) | ATRKCNH2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL20846002 | 0.79 | CYP11B1 (0.40) | ATRKCNH2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL19384213 | 0.77 | MAP4K4 (0.34) | ATRMAP4K4ABL1 | |
| SCHEMBL20848406 | 0.74 | ATR (0.44) | ATRPIK3CDPIK3CAPIK3CGALOX5AP | |
| SCHEMBL20846008 | 0.71 | ATR (0.35) | ATRABL1 | |
| SCHEMBL20849504 | 0.70 | NPSR1 (0.37) | PIK3CDPIK3CAPIK3CGABL1 | |
| SCHEMBL11906430 | 0.69 | ATR (0.64) | ATRCDK5CDK5R1 | |
| SCHEMBL20846004 | 0.69 | KDM4E (0.34) | ATRABL1 | |
| SCHEMBL670030 | 0.69 | HTT (0.37) | ATRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684184-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| WO-2019057723-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | DDT, HPD, PLPBP | ATR 2054/4885KCNH2 1448/4885PIK3CD 552/4885 |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | DDT, HPD, PLPBP | ATR 2054/4885KCNH2 1448/4885PIK3CD 552/4885 |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | DDT, HPD, PLPBP | ATR 2054/4885KCNH2 1448/4885PIK3CD 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.