Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 6/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20845987 | 0.86 | ABL1 (0.35) | KDM4EALDH1A1ABL1TRPA1 | |
| SCHEMBL20846008 | 0.86 | ATR (0.35) | ATRHPGDABL1GRM5GRM1 | |
| SCHEMBL20843706 | 0.81 | GPR119 (0.35) | ATRABL1 | |
| SCHEMBL20846010 | 0.72 | ABL1 (0.35) | ABL1 | |
| SCHEMBL20839264 | 0.72 | CYP11B2 (0.36) | ABL1 | |
| SCHEMBL20848359 | 0.69 | ATR (0.43) | ATRABL1 | |
| SCHEMBL20843729 | 0.68 | ABL1 (0.33) | ABL1 | |
| SCHEMBL19406057 | 0.68 | ABL1 (0.35) | ATRABL1GRM5GRM1 | |
| SCHEMBL19406668 | 0.68 | ABL1 (0.38) | KDM4EHPGDALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL19406221 | 0.67 | PTGES (0.35) | KDM4EHPGDALDH1A1SMN1; SMN2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| EP-3684764-B1 | PYRAZINE-4-CARBAMATE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-10 | — | — | EP | disclosed |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| WO-2019057724-A1 | PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | KDM4E 380/4885ATR 2637/4885HPGD 951/4885 |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | PLPBP, PDXK, HPD | KDM4E 276/4885ATR 2730/4885HPGD 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.