SCHEMBL20849296

SCHEMBL20849296

N#Cc1cccc(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1-c1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)ccc1-n1c2ccccc2c2cc(-c3ccccc3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 4/20 0.33
ICMT O60725 1/20 0.33
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20849298 0.97 TACR1 (0.35) TACR1ICMTRXRARXRGGRIN1
SCHEMBL20849274 0.97 ICMT (0.32) TACR1ICMTGRIN1GRIN2BKDM4E
SCHEMBL20849221 0.94 TACR1 (0.38) TACR1RXRARXRGKDM4E
SCHEMBL20849084 0.94 PTPN5 (0.36) TACR1RXRARXRGGRIN1GRIN2B
SCHEMBL20848536 0.94 AR (0.37) TACR1ICMT
SCHEMBL20849273 0.94 PTPN5 (0.34) ICMTGRIN1GRIN2BKDM4EALDH1A1
SCHEMBL20848990 0.93 KIF11 (0.33) TACR1ICMTGRIN1GRIN2BKDM4E
SCHEMBL21399301 0.93 KIF11 (0.33) TACR1ICMTGRIN1GRIN2BKDM4E
SCHEMBL20849272 0.93 AR (0.34) TACR1ICMTRXRARXRGGRIN1
SCHEMBL20849226 0.93 RXRA (0.35) TACR1ICMTRXRARXRGGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 TACR1 2846/4885ICMT 616/4885RXRA 1822/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 TACR1 2846/4885ICMT 616/4885RXRA 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.