SCHEMBL20850206

SCHEMBL20850206

Cc1ccc(N(c2ccc3c(c2)C(C)(C)c2ccccc2-3)c2ccc3c(c2)C(C)(C)c2cc(C=C(C#N)C#N)sc2-3)cc1C

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850202 0.94 — —
SCHEMBL20850205 0.91 NPC1 (0.31) NPC1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL20850284 0.91 SLC16A3 (0.34) NPC1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL20850390 0.90 — —
SCHEMBL20850098 0.87 SLC16A3 (0.36) NPC1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL20850389 0.87 SLC16A3 (0.32) NPC1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL20850286 0.85 MAPT (0.34) —
SCHEMBL20850386 0.84 — —
SCHEMBL20850391 0.84 MAPT (0.36) NPC1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL20850204 0.84 APP (0.32) NPC1CYP1A2CYP2C9CYP2C19RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 NPC1 3567/4885CYP1A2 75/4885CYP2C9 1406/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 NPC1 3567/4885CYP1A2 75/4885CYP2C9 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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