SCHEMBL20850391

SCHEMBL20850391

CC1(C)c2cc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)ccc2-c2sc(C=C(C#N)C#N)cc21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.36
▸ APP P05067 2/20 0.35
▸ SLC16A3 O15427 1/20 0.32
▸ SLC16A1 P53985 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ LMNA P02545 2/20 0.32
▸ HPGD P15428 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850395 0.99 MAPT (0.37) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850288 0.96 MAPT (0.34) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850098 0.95 SLC16A3 (0.36) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850299 0.94 MAPT (0.32) MAPTAPPNPC1CYP1A2CYP2C9
SCHEMBL20850284 0.91 SLC16A3 (0.34) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850283 0.89 SLC16A3 (0.33) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850286 0.89 MAPT (0.34) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL20850389 0.88 SLC16A3 (0.32) MAPTAPPSLC16A3SLC16A1NPC1
SCHEMBL20850204 0.88 APP (0.32) APPNPC1CYP1A2CYP2C9CYP2C19
SCHEMBL20850205 0.87 NPC1 (0.31) MAPTNPC1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 MAPT 3800/4885APP 1621/4885SLC16A3 3490/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 MAPT 3800/4885APP 1621/4885SLC16A3 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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