SCHEMBL20850277

SCHEMBL20850277

Clc1cnc2c(c1)C1(c3ccccc3-c3ccccc31)c1ccsc1-2

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 4/20 0.46
▸ AKR1A1 P14550 1/20 0.32
▸ AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850164 0.77 PDK2 (0.44) PDK2AKR1A1AKR1B1
SCHEMBL20850142 0.76 PDK2 (0.35) PDK2
SCHEMBL21940539 0.75 PTPRC (0.41) PDK2
SCHEMBL9927262 0.74 PTPRC (0.39) PDK2
SCHEMBL20850470 0.69 HRH1 (0.33) PDK2
SCHEMBL21939620 0.69 PDK2 (0.41) PDK2
SCHEMBL23568056 0.66 PDK2 (0.44) PDK2
SCHEMBL31513486 0.66 PDK2 (0.44) PDK2
SCHEMBL23568673 0.66 PDK2 (0.44) PDK2
SCHEMBL12306496 0.65 PDK2 (0.56) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 PDK2 828/4885AKR1A1 1464/4885AKR1B1 2143/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 PDK2 828/4885AKR1A1 1464/4885AKR1B1 2143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback