SCHEMBL20850470

SCHEMBL20850470

Clc1ccc2c(c1)C1(c3cccnc3-c3ncccc31)c1ccsc1-2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HRH1 P35367 5/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ ADRB2 P07550 1/20 0.33
▸ CHRM2 P08172 1/20 0.33
▸ CHRM4 P08173 1/20 0.33
▸ ABCB1 P08183 1/20 0.33
▸ HTR1A P08908 1/20 0.33
▸ CHRM5 P08912 1/20 0.33
▸ ADRA2A P08913 1/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ DRD2 P14416 1/20 0.33
▸ ADRA2B P18089 1/20 0.33
▸ ADRA2C P18825 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ DRD1 P21728 1/20 0.33
▸ TBXA2R P21731 1/20 0.33
▸ DRD4 P21917 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850164 0.82 PDK2 (0.44) MEN1LMNAOPRK1KMT2APDK2
SCHEMBL22609096 0.76 PDK2 (0.44) HRH1MEN1LMNAADRB2CHRM2
SCHEMBL29395626 0.76 PDK2 (0.44) HRH1MEN1LMNAADRB2CHRM2
SCHEMBL20881134 0.70 PDK2 (0.34) PDK2
SCHEMBL20850277 0.69 PDK2 (0.46) PDK2
SCHEMBL20850099 0.69 CASP3 (0.37) LMNAHTR2AHTR2CPDK2CYP11B2
SCHEMBL20089623 0.69 PDK2 (0.45) HRH1MEN1LMNAADRB2CHRM2
SCHEMBL11990870 0.69 PDK2 (0.42) MEN1LMNAKMT2APDK2ALDH1A1
SCHEMBL10021903 0.66 PDK2 (0.56) KMT2APDK2PTAFRNPC1ALDH1A1
SCHEMBL577401 0.66 PDK2 (0.41) MEN1KMT2APDK2PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 — — EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 HRH1 430/4885MEN1 3080/4885LMNA 4775/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 HRH1 430/4885MEN1 3080/4885LMNA 4775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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