SCHEMBL20850307

SCHEMBL20850307

Cc1ccc(N(c2cnc3c(c2)C(C)(C)c2cc(C=C(C#N)C#N)sc2-3)c2ccc3ccccc3c2)cc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PABPC1 P11940 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850069 0.92 APP (0.32) KDM4EMEN1MAPTPABPC1KMT2A
SCHEMBL20850305 0.92 — —
SCHEMBL20850346 0.90 APP (0.31) —
SCHEMBL20850410 0.90 MAPT (0.34) MEN1MAPTKMT2A
SCHEMBL20850071 0.87 MEN1 (0.36) MEN1MAPTKMT2A
SCHEMBL20850388 0.87 MEN1 (0.32) KDM4EMEN1MAPTPABPC1KMT2A
SCHEMBL20850078 0.86 MAPT (0.36) MEN1MAPTKMT2A
SCHEMBL20850375 0.84 MEN1 (0.32) KDM4EMEN1MAPTPABPC1KMT2A
SCHEMBL20850079 0.84 MAPT (0.32) MEN1MAPTKMT2A
SCHEMBL20850308 0.83 MEN1 (0.32) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 — — EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 — — EP disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 KDM4E 2895/4885MEN1 3080/4885MAPT 3800/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 KDM4E 2895/4885MEN1 3080/4885MAPT 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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