SCHEMBL20850340

SCHEMBL20850340

CC1(C)c2cc(N(c3ccccc3)c3ccc4ccccc4c3)ccc2-c2sc(/C=C/C=C(C#N)C#N)cc21

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 5/20 0.34
▸ SNCA P37840 3/20 0.32
▸ MEN1 O00255 2/20 0.30
▸ KMT2A Q03164 2/20 0.30
▸ CRHBP P24387 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ CRHR2 Q13324 1/20 0.30
▸ KEAP1 Q14145 1/20 0.30
▸ NFE2L2 Q16236 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850093 0.95 APP (0.33) APPSNCA
SCHEMBL20850338 0.94 APP (0.33) APPSNCAMEN1KMT2ACRHBP
SCHEMBL20850283 0.89 SLC16A3 (0.33) APPMEN1KMT2AMAPT
SCHEMBL20850204 0.86 APP (0.32) APPMEN1KMT2A
SCHEMBL20850388 0.84 MEN1 (0.32) APPMEN1KMT2AHTTMAPT
SCHEMBL20850098 0.83 SLC16A3 (0.36) APPMEN1KMT2ACRHBPHTT
SCHEMBL20850346 0.82 APP (0.31) APPSNCA
SCHEMBL20850386 0.80 — —
SCHEMBL20850284 0.79 SLC16A3 (0.34) APPMEN1KMT2ACRHBPHTT
SCHEMBL20850395 0.79 MAPT (0.37) APPMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 APP 1621/4885SNCA 1341/4885MEN1 3080/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 APP 1621/4885SNCA 1341/4885MEN1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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