SCHEMBL20850283

SCHEMBL20850283

CC1(C)c2cc(N(c3ccccc3)c3ccc4ccccc4c3)ccc2-c2sc(C=C(C#N)C#N)cc21

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLC16A3 O15427 1/20 0.33
▸ SLC16A1 P53985 1/20 0.33
▸ MAPT P10636 1/20 0.32
▸ APP P05067 2/20 0.32
▸ NPC1 O15118 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ MEN1 O00255 2/20 0.30
▸ KMT2A Q03164 2/20 0.30
▸ LMNA P02545 1/20 0.30
▸ BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850204 0.97 APP (0.32) APPNPC1CYP1A2CYP2C9CYP2C19
SCHEMBL20850388 0.94 MEN1 (0.32) MAPTAPPMEN1KMT2A
SCHEMBL20850098 0.94 SLC16A3 (0.36) SLC16A3SLC16A1MAPTAPPNPC1
SCHEMBL20850386 0.91 — —
SCHEMBL20850284 0.90 SLC16A3 (0.34) SLC16A3SLC16A1MAPTAPPNPC1
SCHEMBL20850395 0.90 MAPT (0.37) SLC16A3SLC16A1MAPTAPPNPC1
SCHEMBL20850391 0.89 MAPT (0.36) SLC16A3SLC16A1MAPTAPPNPC1
SCHEMBL20850340 0.89 APP (0.34) MAPTAPPMEN1KMT2A
SCHEMBL20850203 0.89 KDM4E (0.31) MAPTLMNA
SCHEMBL20850389 0.88 SLC16A3 (0.32) SLC16A3SLC16A1MAPTAPPNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 SLC16A3 3490/4885SLC16A1 3527/4885MAPT 3800/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 SLC16A3 3490/4885SLC16A1 3527/4885MAPT 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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