SCHEMBL20850438

SCHEMBL20850438

COC(=O)c1cc(Cl)cnc1-c1cccs1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.49
▸ KDM4E B2RXH2 2/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ MEN1 O00255 2/20 0.48
▸ MAPT P10636 6/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ THRB P10828 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ NPC1 O15118 1/20 0.44
▸ NR4A2 P43354 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ POLQ O75417 1/20 0.43
▸ GRIN2D O15399 1/20 0.42
▸ GRIN3B O60391 1/20 0.42
▸ GRIN1 Q05586 1/20 0.42
▸ GRIN2A Q12879 1/20 0.42
▸ GRIN2B Q13224 1/20 0.42
▸ GRIN2C Q14957 1/20 0.42
▸ GRIN3A Q8TCU5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8394454 0.79 JUN (0.57) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL20850165 0.78 MAPT (0.53) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL18816928 0.78 DHODH (0.52) KMT2AKDM4EMEN1MAPTNR4A2
SCHEMBL25545582 0.76 KMT2A (0.49) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL30295565 0.76 KMT2A (0.49) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL1610957 0.75 KMT2A (0.55) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL30171520 0.75 PTGS1 (0.51) KDM4ETDP1NPC1ALDH1A1POLB
SCHEMBL28405722 0.75 PTGS1 (0.51) KDM4ETDP1NPC1ALDH1A1POLB
SCHEMBL25547359 0.75 POLQ (0.54) KMT2AKDM4ERAB9AHSD17B10MEN1
SCHEMBL25546300 0.75 MAPT (0.51) KMT2AKDM4ERAB9AHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 — — EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 — — EP disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 KMT2A 2556/4885KDM4E 2895/4885RAB9A 3973/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 KMT2A 2556/4885KDM4E 2895/4885RAB9A 3973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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