Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20850789 | 0.77 | KDM4E (0.39) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL20850795 | 0.77 | KDM4E (0.39) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL22461930 | 0.74 | FDPS (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL19819318 | 0.74 | KDM4E (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL19819319 | 0.74 | KDM4E (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL6879318 | 0.74 | KDM4E (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL7498448 | 0.74 | FDPS (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL27504819 | 0.73 | KDM4E (0.35) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL28057200 | 0.72 | KEAP1 (0.39) | KDM4ECYP1A2CYP2D6CYP2C19SLC6A3 | |
| SCHEMBL5447760 | 0.70 | KDM4E (0.42) | FDPSKDM4ENPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066076-B1 | PROCESS FOR THE PREPARATION OF METHYLPHENIDATE AND PHARMACEUTICAL SALTS THEREOF | NORAMCO INC (US) | 2019-03-27 | — | — | EP | disclosed |