Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712678 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBHTTGAA | |
| SCHEMBL23926506 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL3649421 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHTTCRHR1 | |
| SCHEMBL27912918 | 0.80 | GLO1 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL27864136 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBGAAMEN1 | |
| SCHEMBL3653734 | 0.76 | GLO1 (0.48) | ALDH1A1MAPTPOLBGAAPKM | |
| SCHEMBL23926485 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBHTTGAA | |
| SCHEMBL23926476 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBHTTMAPK1 | |
| SCHEMBL30794117 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTMAPK1MEN1 | |
| SCHEMBL15712849 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |