Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395674 | 0.83 | ALOX5 (0.41) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL23926506 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL15712849 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL3649421 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL23926503 | 0.79 | ENPP3 (0.47) | ALDH1A1KMT2AENPP3ENPP1GAA | |
| SCHEMBL15712678 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2AGAAMEN1POLB | |
| SCHEMBL23926476 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2AENPP3ENPP1MEN1 | |
| SCHEMBL20850832 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2AGAAMEN1POLB | |
| SCHEMBL27912918 | 0.77 | GLO1 (0.47) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL30794117 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102281919-A | Inhibitors of diacylglycerol acyltransferase | — | 2011-12-14 | — | — | CN | disclosed |