Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488 | 0.79 | LMNA (0.50) | RECQLLMNAMAOAMAPTGAA | |
| SCHEMBL22172517 | 0.78 | MAPT (0.36) | RECQLLMNAMAOAMAPTGAA | |
| SCHEMBL10821119 | 0.72 | LMNA (0.52) | RECQLLMNAMAPTGAAALDH1A1 | |
| SCHEMBL18384637 | 0.72 | PDE4A (0.47) | RECQLLMNAMAOAMAPTALDH1A1 | |
| SCHEMBL14656256 | 0.71 | KDM4E (0.50) | RECQLLMNAMAOAMAPTGAA | |
| Hydrochloric Acid SCHEMBL22157868 | 0.70 | GAA (0.37) | RECQLLMNAMAPTGAAALDH1A1 | |
| SCHEMBL18384689 | 0.69 | LMNA (0.43) | RECQLLMNAMAOAMAPTGAA | |
| SCHEMBL18384665 | 0.69 | PDE4A (0.47) | RECQLLMNAMAOAMAPTALDH1A1 | |
| SCHEMBL22261473 | 0.68 | MAPT (0.44) | RECQLLMNAMAOAMAPTGAA | |
| SCHEMBL12526833 | 0.68 | KDM4E (0.39) | RECQLLMNAMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019059344-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | 大日本住友製薬株式会社 | 2019-03-28 | — | — | WO | disclosed |