Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851725 | 0.68 | RECQL (0.49) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL5584152 | 0.68 | KDM4E (0.65) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL2142605 | 0.67 | ALDH1A1 (0.42) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL15920417 | 0.66 | POLH (0.58) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28661959 | 0.65 | ALDH1A1 (0.41) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL1896215 | 0.63 | LMNA (0.66) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL12858762 | 0.62 | KDM4E (1.00) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL14656256 | 0.61 | KDM4E (0.50) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL3954485 | 0.61 | LMNA (0.46) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL20189138 | 0.60 | LMNA (0.54) | MAPTGAAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686182-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-07-29 | — | — | EP | disclosed |
| CN-111295368-A | Chemically activated water soluble prodrugs | 大日本住友制药株式会社 | 2020-06-16 | — | — | CN | disclosed |