SCHEMBL600578

SCHEMBL600578

Cc1ccc(C(=O)CC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.83
NPC1 O15118 6/20 0.83
KMT2A Q03164 6/20 0.83
MEN1 O00255 5/20 0.83
MAPT P10636 3/20 0.73
GSK3B P49841 1/20 0.67
ALDH1A1 P00352 5/20 0.59
LMNA P02545 3/20 0.59
CES1 P23141 2/20 0.59
CES2 O00748 1/20 0.59
GAA P10253 1/20 0.58
HPGD P15428 3/20 0.58
HTT P42858 3/20 0.58
KDM4E B2RXH2 2/20 0.58
PLA2G1B P04054 1/20 0.58
XBP1 P17861 1/20 0.58
ALOX12 P18054 1/20 0.58
KCNH2 Q12809 1/20 0.58
ATG4B Q9Y4P1 1/20 0.58
SMN1; SMN2 Q16637 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16127292 0.91 RAB9A (0.70) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL269482 0.91 NPC1 (1.00) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL3035986 0.88 NPC1 (0.67) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL4842224 0.88 NPC1 (0.73) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL20853597 0.88 NPC1 (0.67) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL7630221 0.87 NPC1 (0.66) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL14186126 0.87 RAB9A (0.66) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL12270652 0.87 RAB9A (0.66) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL1200125 0.86 NPC1 (0.64) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL11813102 0.86 NPC1 (0.64) RAB9ANPC1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1635777-B1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION MERCK PATENT GMBH (DE) 2012-06-06 EP claimed
US-8003082-B2 Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2011-08-23 US claimed
US-20070059258-A1 Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2007-03-15 US claimed
US-7166273-B2 Photo stable organic sunscreen compositions EMD CHEMICALS, INC. (US) 2007-01-23 US claimed
EP-1635777-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION MERCK PATENT GmbH (DE) 2006-03-22 EP claimed
WO-2004105712-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION MERCK PATENT GMBH (DE) 2004-12-09 WO claimed
US-20040247536-A1 Photo stable organic sunscreen compositions EMD CHEMICALS, INC. 2004-12-09 US claimed
US-20040057918-A1 For use in cosmetic and/or dermatological formulations SOCIETE L'OREAL S.A. (FR) 2004-03-25 US claimed
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION AKDENIZ CHEMSON ADDITIVES A.G. (AT) 2026-05-28 US disclosed
EP-4605200-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION Akdeniz Chemson Additives AG (AT) 2025-08-27 EP disclosed
CN-120076911-A Method and device for producing a stabilizer composition in particulate form and stabilizer composition produced thereby 阿登尼斯开米森添加剂股份公司 2025-05-30 CN disclosed
US-12179977-B2 Film for food packaging, stretch film for food packaging, film for automatic packaging machine for food packaging, and method for packaging food MITSUBISHI CHEMICAL CORPORATION (JP) 2024-12-31 US disclosed
WO-2024256407-A1 METHOD FOR TREATING HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2024-12-19 WO disclosed
EP-4477694-A1 METHOD FOR TREATING HALOGENATED POLYMERS Baerlocher GmbH (DE) 2024-12-18 EP disclosed
US-4416797-A Chlorinated organic compounds having their resistance to deterioration enhanced by 1,3-dicarbonyl compounds ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-11-22 US disclosed
EP-0063180-A1 Beta-diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-10-27 EP disclosed
US-4282141-A DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1981-08-04 US disclosed
US-4252698-A A OVERBASED SULFONATE OR PHENOLATE, AND A 1,3-DIKETONE FOR VINYL CHLORIDE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1981-02-24 US disclosed
US-4244848-A HEAT RESISTANT STABILIZERS COMPRISING AT LEAST ONE ZINC, DIALKYLTIN, ALKALI METAL OR ALKALINE EARTH METAL ORGANIC PHOSPHATE ESTER SALT AND AT LEAST ONE B-DIKETONE ARGUS CHEMICAL CORPORATION (US) 1981-01-13 US disclosed
US-4036605-A CATALYZING OXIDATION OF HYDROCARBONS WITH A B-KETOENOLATE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070059258-A1 Photostable organic sunscreen composition SUN2, ERCC1, PPOX RAB9A 2772/4885NPC1 1325/4885KMT2A 3272/4885
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION GRN, IL36G, GMNN RAB9A 2868/4885NPC1 1816/4885KMT2A 4384/4885
US-20040057918-A1 For use in cosmetic and/or dermatological formulations DSG1, TYR, CUTA RAB9A 2773/4885NPC1 4328/4885KMT2A 2343/4885
US-20040247536-A1 Photo stable organic sunscreen compositions SUN2, CCNB1, TYR RAB9A 1324/4885NPC1 2349/4885KMT2A 3170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.