Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851803 | 0.87 | ALOX15 (0.47) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL20851732 | 0.85 | ALOX15 (0.53) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL24228266 | 0.77 | ALOX15 (0.57) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL20851731 | 0.76 | ALOX5 (0.58) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL1105238 | 0.76 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL5595508 | 0.76 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9016180 | 0.76 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9671304 | 0.75 | ALOX15 (0.58) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9671310 | 0.75 | ALOX15 (0.58) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL8985109 | 0.74 | ALOX15 (0.55) | ALOX15ALOX5TRPA1RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057600-A1 | NEW INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP ASSETS B.V. (NL) | 2019-03-28 | — | — | WO | disclosed |