Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851804 | 0.85 | ALOX15 (0.48) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL20851803 | 0.84 | ALOX15 (0.47) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL1105235 | 0.83 | MAPT (0.41) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9016180 | 0.81 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL1105238 | 0.81 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL5595508 | 0.81 | ALOX15 (0.60) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9671310 | 0.80 | ALOX15 (0.58) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL9671304 | 0.80 | ALOX15 (0.58) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL8985112 | 0.79 | ALOX15 (0.55) | ALOX15ALOX5TRPA1RARBRARG | |
| SCHEMBL8985109 | 0.79 | ALOX15 (0.55) | ALOX15ALOX5TRPA1RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169590-A1 | INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP ASSETS BV (NL) | 2022-06-02 | — | — | US | disclosed |
| US-20200283368-A1 | NEW INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP ASSETS B.V. (NL) | 2020-09-10 | — | — | US | disclosed |
| WO-2019057600-A1 | NEW INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP ASSETS B.V. (NL) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169590-A1 | INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | COASY, TTPA, FASN | ALOX15 246/4885ALOX5 265/4885TRPA1 4388/4885 |
| US-20200283368-A1 | NEW INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | COASY, SQLE, DOHH | ALOX15 237/4885ALOX5 130/4885TRPA1 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.