SCHEMBL20853073

SCHEMBL20853073

C(=N/c1ccc(N2CCOCC2)cc1)\c1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.64
MAOA P21397 2/20 0.58
MAPT P10636 11/20 0.53
MEN1 O00255 7/20 0.53
KMT2A Q03164 7/20 0.53
ALDH1A1 P00352 6/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
NPC1 O15118 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPK1 P28482 1/20 0.53
MAOB P27338 1/20 0.52
KDM4E B2RXH2 5/20 0.52
THRB P10828 1/20 0.52
TDP1 Q9NUW8 2/20 0.51
POLB P06746 1/20 0.51
HPGD P15428 1/20 0.51
ALOX12 P18054 1/20 0.51
HTT P42858 1/20 0.51
PTK2B Q14289 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13294351 0.80 ALDH1A1 (0.49) NR4A1MAOAMAPTMEN1KMT2A
Bromide SCHEMBL3691409 0.77 NR4A1 (0.92) NR4A1MAOAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL3691373 0.77 NR4A1 (0.92) NR4A1MAOAMAPTMEN1KMT2A
Bromide SCHEMBL3698509 0.77 NR4A1 (0.92) NR4A1MAOAMAPTMEN1KMT2A
Bromide SCHEMBL3692019 0.77 NR4A1 (0.92) NR4A1MAOAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL3696873 0.77 NR4A1 (0.92) NR4A1MAOAMAPTMEN1KMT2A
SCHEMBL301198 0.75 MAOA (1.00) NR4A1MAOAMAPTMEN1KMT2A
SCHEMBL2646403 0.75 MAOA (1.00) NR4A1MAOAMAPTMEN1KMT2A
SCHEMBL30529897 0.75 MAOA (1.00) NR4A1MAOAMAPTMEN1KMT2A
SCHEMBL13754809 0.75 MAOA (1.00) NR4A1MAOAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611720-B2 Composition for preventing or treating hair loss including benzene diamine derivative UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2020-04-07 US disclosed
US-20190092717-A1 COMPOSITION FOR PREVENTING OR TREATING HAIR LOSS INCLUDING BENZENE DIAMINE DERIVATIVE UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092717-A1 COMPOSITION FOR PREVENTING OR TREATING HAIR LOSS INCLUDING BENZENE DIAMINE DERIVATIVE DACH1, TYR, SAT1 NR4A1 1760/4885MAOA 924/4885MAPT 2036/4885
US-10611720-B2 Composition for preventing or treating hair loss including benzene diamine derivative DACH1, TYR, SAT1 NR4A1 1760/4885MAOA 924/4885MAPT 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.