Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095474 | 0.82 | KDM4E (0.40) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL20654244 | 0.81 | CNR2 (0.39) | KDM4EHSD17B10MAPTCNR2CNR1 | |
| SCHEMBL26506743 | 0.81 | KDM4E (0.39) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL22892626 | 0.80 | KDM4E (0.34) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL13637910 | 0.77 | GPR3 (0.46) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL14202563 | 0.76 | TUBB4A (0.48) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL13014905 | 0.75 | L3MBTL1 (0.45) | KDM4ELMNACASP1MEN1KMT2A | |
| SCHEMBL24848671 | 0.73 | KDM4E (0.36) | KDM4EGPR3LMNACASP1MEN1 | |
| SCHEMBL14045624 | 0.73 | CNR2 (0.46) | KDM4EGPR3MEN1KMT2ATSHR | |
| SCHEMBL15450945 | 0.73 | CYP1A2 (0.51) | KDM4EGPR3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |