Methacrylic Acid

Methacrylic Acid

SCHEMBL208533

C=C(C)C(=O)O.CC=COC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL9154994 0.88 THRB (0.31) THRB
SCHEMBL235915 0.86
Methacrylic Acid SCHEMBL8822896 0.85 THRB (0.32) THRB
Methacrylic Acid SCHEMBL28626299 0.77 THRB (0.33) THRB
Methacrylic Acid SCHEMBL28737039 0.76 THRB (0.38) THRB
Methacrylic Acid SCHEMBL672619 0.76 THRB (0.38) THRB
Methacrylic Acid SCHEMBL2530282 0.76 THRB (0.38) THRB
Methacrylic Acid SCHEMBL534405 0.76 THRB (0.32) THRB
Methacrylic Acid SCHEMBL6700142 0.76 THRB (0.32) THRB
Methacrylic Acid SCHEMBL31316646 0.75 THRB (0.50) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1128191-B1 Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain HOYA HEALTHCARE CORP (JP) 2005-04-20 EP claimed
US-6602930-B2 Excellent flexibility and oxygen permeability HOYA HEALTHCARE CORPORATION (JP) 2003-08-05 US claimed
US-20020005933-A1 Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain HOYA CORPORATION (JP) 2002-01-17 US claimed
EP-1128191-A2 Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain HOYA HEALTHCARE CORPORATION (JP) 2001-08-29 EP claimed
WO-2020147830-A1 OCULAR LENS, PHARMACEUTICAL COMPOSITION, AND USES THEREOF GOLDRED NANOBIOTECH CO., LTD. (CN) 2020-07-23 WO disclosed
EP-1854490-B1 INTRAOCULAR LENS AND METHOD OF PRODUCING THE SAME HOYA CORP (JP) 2015-04-01 EP disclosed
EP-1810700-B1 METHOD OF PRODUCING SURFACE-TREATED INTRAOCULAR LENS AND INTRAOCULAR LENS FOR INHIBITING SECONDARY CATARACT HOYA CORP (JP) 2015-04-01 EP disclosed
EP-1857477-B1 (METH)ACRYLATE COMPOUND, PROCESS FOR PRODUCTION OF THE COMPOUND, (METH)ACRYLATE COPOLYMER, PROCESS FOR PRODUCTION OF THE COPOLYMER, AND SOFT INTRAOCULAR LENS HOYA CORP (JP) 2012-06-27 EP disclosed
US-8088314-B2 Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract HOYA CORPORATION (JP) 2012-01-03 US disclosed
US-7892284-B2 Intraocular lens and process for producing the same HOYA CORPORATION (JP) 2011-02-22 US disclosed
US-7714090-B2 (Meth)acrylate compound and process for the production thereof, (meth)acrylate copolymer and process for the production of (meth)acrylate copolymer, and soft intraocular lens HOYA CORPORATION (JP) 2010-05-11 US disclosed
US-20090024115-A1 Process for producing surface-treated intraocular lens and intraocular lens capable of inhibiting secondary cataract HOYA Medical Singapore Pte. Ltd. (SG) 2009-01-22 US disclosed
US-5194542-A Crosslinked Fluoroacrylate Copolymer HOYA CORPORATION (JP) 1993-03-16 US disclosed
EP-0497369-A2 Contact lens material and contact lens HOYA CORPORATION (JP) 1992-08-05 EP disclosed
EP-0461270-A1 CONTACT LENS MATERIAL AND CONTACT LENS HOYA CORPORATION (JP) 1991-12-18 EP disclosed
EP-0448978-A2 Material for contact lenses and contact lenses prepared therefrom HOYA CORPORATION (JP) 1991-10-02 EP disclosed
EP-0446372-A1 CONTACT LENS HOYA CORPORATION (JP) 1991-09-18 EP disclosed
EP-0436727-A1 CONTACT LENS HOYA CORPORATION (JP) 1991-07-17 EP disclosed
US-5008354-A Consisting of fluoroalkyloxyalkylene (meth)acrylate polymer; having no water absorbability HOYA CORPORATION (JP) 1991-04-16 US disclosed
EP-0340636-A2 Contact lens HOYA CORPORATION (JP) 1989-11-08 EP disclosed