Methacrylic Acid

Methacrylic Acid

SCHEMBL672619

C=C(C)C(=O)O.CC(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
TET2 Q6N021 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL2530282 1.00 THRB (0.38) THRBTET2
Acetic Acid SCHEMBL29256055 0.88 THRB (0.43) THRB
Acetic Acid SCHEMBL29256049 0.86 THRB (0.39) THRB
Methacrylic Acid SCHEMBL28737039 0.85 THRB (0.38) THRB
Methacrylic Acid SCHEMBL31316646 0.84 THRB (0.50) THRBTET2
Perflubutane SCHEMBL5248074 0.82 THRB (0.46) THRBTET2
SCHEMBL3145629 0.82 LMNA (0.35) THRB
SCHEMBL2378730 0.82 LMNA (0.35) THRB
SCHEMBL7886337 0.82 LMNA (0.35) THRB
SCHEMBL11588700 0.82 LMNA (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833419-B2 Fluorine-modified comb polymers based on acryloydimethyltaurine acid CLARIANT GMBH (DE) 2004-12-21 US claimed
US-20040116634-A1 Fluorine-modified comb polymers based on acryloydimethyltaurine acid CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-17 US claimed
US-8187581-B2 Copolymers from acryloyldimethyltaurine or an acryloyldimethyltaurate, olefinically unsaturated, noncationic, crosslinking comonomer, olefinically unsaturated, cationic comonomer having oxygen, nitrogen, sulfur or phosphorus, silicon-containing component, macromonomer having oxygen, nitrogen, sulfur CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2012-05-29 US disclosed
US-8062630-B2 Polymer from acryloyldimethyltaurine, olefinically unsaturated, cationic comonomer, unsaturated, noncationic, crosslinking comonomer, an unsaturated silicon containing comonomer, a crosslinking macromonomer; a thickener, bodying agent, emulsifier, dispersant and/or stabilizer CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2011-11-22 US disclosed
US-20110257016-A1 Gel Formulations that are Stable for Storage, Comprising at Least Two Substantially Unmixed Hydrogels BASF SE (DE) 2011-10-20 US disclosed
US-7943157-B2 copolymer based on acryloxydimethyltaurine; water soluble, water swelling CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2011-05-17 US disclosed
US-7566763-B2 Stable dispersion concentrates CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2009-07-28 US disclosed
US-20080207773-A1 Cosmetic, pharmaceutical and dermatological products CLARIANT GMBH (DE) 2008-08-28 US disclosed
US-7399478-B2 Cosmetic, pharmaceutical and dermatological products CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2008-07-15 US disclosed
US-7393520-B2 Decorative cosmetic and dermatological products CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2008-07-01 US disclosed
US-20080107617-A1 Surfactant-containing cosmetic, dermatological and pharmaceutical agents CLARIANT PRODUKTE (DEUTSCHLAND) GMBH 2008-05-08 US disclosed
US-20040115149-A1 Cosmetic, pharmaceutical and dermatological products containing an electrolyte CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-17 US disclosed
US-20040115148-A1 Acid cosmetic, dermatological and pharmaceutical agents CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-17 US disclosed
US-20040115157-A1 Cosmetic and dermatological hair-treatment agents CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-17 US disclosed
US-20040109838-A1 Compositions containing copolymers based on acryloyldimethyl aminoethylsulfonic acid and synergistic additives CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-10 US disclosed
US-20040109836-A1 Surfactant-free cosmetic, dermatological and pharmaceutical agents CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-10 US disclosed
US-20040109835-A1 Cosmetic, pharmaceutical and dermatological products CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-06-10 US disclosed
US-20040096409-A1 Comb copolymers of 2-acrylamido-2-methylpropanesulfonic acid or salts CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-05-20 US disclosed
US-20040091444-A1 Decorative cosmetic and dermatological products CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-05-13 US disclosed
US-20030232028-A1 Stable dispersion concentrates CLARIANT GMBH 2003-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040109835-A1 Cosmetic, pharmaceutical and dermatological products ATIC, FFAR3, TPMT THRB 4539/4885TET2 1067/4885
US-20040096409-A1 Comb copolymers of 2-acrylamido-2-methylpropanesulfonic acid or salts PAICS, MTHFD2, DIMT1 THRB 3788/4885TET2 1018/4885
US-20110257016-A1 Gel Formulations that are Stable for Storage, Comprising at Least Two Substantially Unmixed Hydrogels HSP90AA1, HSP90B1, HSPA1B THRB 4426/4885TET2 4429/4885
US-20040091444-A1 Decorative cosmetic and dermatological products CUTA, ESD, ATIC THRB 4746/4885TET2 682/4885
US-20040109838-A1 Compositions containing copolymers based on acryloyldimethyl aminoethylsulfonic acid and synergistic additives TPMT, ATIC, SLC6A12 THRB 2704/4885TET2 3007/4885
US-20040109836-A1 Surfactant-free cosmetic, dermatological and pharmaceutical agents FFAR3, SGMS1, SGMS2 THRB 1850/4885TET2 2934/4885
US-20030232028-A1 Stable dispersion concentrates FUS, CFD, C9 THRB 4469/4885TET2 2003/4885
US-20080107617-A1 Surfactant-containing cosmetic, dermatological and pharmaceutical agents SGMS1, SUCLG1, SGMS2 THRB 4608/4885TET2 2714/4885
US-20080207773-A1 Cosmetic, pharmaceutical and dermatological products TPMT, FFAR3, MTHFD2 THRB 4490/4885TET2 845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.