Acrylic Acid

Acrylic Acid

SCHEMBL9154994

C=CC(=O)O.CC=COC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL208533 0.88 THRB (0.31) THRB
Acrylic Acid SCHEMBL9155014 0.86 THRB (0.33) THRB
SCHEMBL235915 0.86
Acrylic Acid SCHEMBL28499334 0.76 THRB (0.38) THRB
Methacrylic Acid SCHEMBL8822896 0.76 THRB (0.32) THRB
SCHEMBL9483747 0.73
SCHEMBL6693176 0.73
SCHEMBL7899865 0.73 TSHR (0.35) THRB
SCHEMBL347671 0.73 TSHR (0.35) THRB
SCHEMBL4893018 0.73 TSHR (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0448978-B1 Material for contact lenses and contact lenses prepared therefrom HOYA CORP (JP) 1995-02-01 EP disclosed
EP-0340636-B1 Contact lens HOYA CORP (JP) 1994-06-29 EP disclosed
EP-0448978-A2 Material for contact lenses and contact lenses prepared therefrom HOYA CORPORATION (JP) 1991-10-02 EP disclosed
US-5008354-A Consisting of fluoroalkyloxyalkylene (meth)acrylate polymer; having no water absorbability HOYA CORPORATION (JP) 1991-04-16 US disclosed
EP-0340636-A2 Contact lens HOYA CORPORATION (JP) 1989-11-08 EP disclosed