SCHEMBL208548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL209669	0.90	MEN1 (0.45)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL209541	0.89	DRD2 (0.50)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL210676	0.89	AURKA (0.42)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL209448	0.88	POLB (0.52)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL4757112	0.84	DRD2 (0.38)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL4754624	0.83	PPARD (0.43)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL209615	0.82	MAPT (0.45)	POLBL3MBTL1ALDH1A1MAPTRPS6KB1
	SCHEMBL209883	0.81	SIGMAR1 (0.46)	L3MBTL1ALDH1A1MAPTNPBWR1MCHR1
	SCHEMBL19674399	0.80	RPS6KB1 (0.33)	POLBL3MBTL1ALDH1A1MAPTNPBWR1
	SCHEMBL207138	0.80	NPC1 (0.45)	POLBALDH1A1MAPTNPBWR1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.