Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | DRD4 | P21917 | 6/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757730 | 0.88 | DRD2 (0.38) | DRD2DRD4DRD3POLBL3MBTL1 | |
| SCHEMBL210676 | 0.86 | AURKA (0.42) | DRD2DRD4DRD3POLBL3MBTL1 | |
| SCHEMBL208548 | 0.84 | POLB (0.53) | POLBL3MBTL1ALDH1A1MAPTNPBWR1 | |
| SCHEMBL209669 | 0.83 | MEN1 (0.45) | POLBL3MBTL1ALDH1A1MAPTNPBWR1 | |
| SCHEMBL209541 | 0.83 | DRD2 (0.50) | DRD2DRD4DRD3POLBL3MBTL1 | |
| SCHEMBL4754624 | 0.79 | PPARD (0.43) | POLBL3MBTL1GNRHRALDH1A1MAPT | |
| SCHEMBL209615 | 0.78 | MAPT (0.45) | POLBL3MBTL1ALDH1A1MAPTRPS6KB1 | |
| SCHEMBL207138 | 0.78 | NPC1 (0.45) | POLBGNRHRALDH1A1MAPTNPBWR1 | |
| SCHEMBL210615 | 0.76 | KDM4E (0.44) | L3MBTL1ALDH1A1MAPTNPBWR1MCHR1 | |
| SCHEMBL207989 | 0.76 | AURKA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |