SCHEMBL20855643

SCHEMBL20855643

CC(C)(C)OC(=O)CSCc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.45
PPARA Q07869 9/20 0.45
LMNA P02545 1/20 0.44
PPARD Q03181 2/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
BLM P54132 1/20 0.40
ESR1 P03372 1/20 0.40
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA13 Q8N1Q1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19403466 0.87 PPARG (0.54) PPARGPPARALMNAPPARD
SCHEMBL19403377 0.85 PPARG (0.55) PPARGPPARALMNAMEN1KMT2A
SCHEMBL19385925 0.85 TP53 (0.53) PPARGPPARALMNAMEN1KMT2A
SCHEMBL19385923 0.85 PPARG (0.56) PPARGPPARALMNAPPARDHTT
SCHEMBL19403370 0.84 PPARG (0.56) PPARGPPARALMNAKMT2A
SCHEMBL1283948 0.79 CA2 (0.50) LMNABLMESR1CTSSCTSK
SCHEMBL4597724 0.78 ALDH1A1 (0.44) MEN1KMT2ACA2MIF
SCHEMBL12689909 0.76 PPARG (0.43) PPARGPPARAPPARDKMT2ACTSS
SCHEMBL1587126 0.76 MEN1 (0.45) LMNAMEN1KMT2ABLMESR1
SCHEMBL1270437 0.74 HTT (0.62) MEN1KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710424-A1 COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS Fraunhofer Gesellschaft zur Förderung der Angewand (DE) 2020-09-23 EP disclosed
EP-3688081-A1 METHOD FOR STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM Fraunhofer Gesellschaft zur Förderung der Angewand (DE) 2020-08-05 EP disclosed
WO-2019063550-A1 METHOD FOR STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2019-04-04 WO disclosed