SCHEMBL1283948

SCHEMBL1283948

CC(C)(C)OC(=O)Cc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CAMK2A Q9UQM7 1/20 0.50
SENP1 Q9P0U3 1/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
ESR1 P03372 3/20 0.45
BLM P54132 1/20 0.44
ESRRB O95718 1/20 0.43
ESRRG P62508 1/20 0.43
ESR2 Q92731 2/20 0.42
KDM4E B2RXH2 1/20 0.42
F13A1 P00488 1/20 0.42
CTBP2 P56545 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
RIPK1 Q13546 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951952 0.85 HSD17B3 (0.48) ESR1KDM4EMIFLMNA
SCHEMBL19085086 0.85 MTNR1A (0.47) MTNR1AMTNR1BCYP4F2CYP4A11RIPK1
SCHEMBL21554546 0.85 CA2 (0.50) CA2CAMK2AMTNR1AMTNR1BKDM4E
SCHEMBL7517689 0.85 HPGD (0.50) MTNR1AMTNR1BCTBP2CYP4F2CYP4A11
SCHEMBL16447010 0.83 MTNR1A (0.46) MTNR1AMTNR1BCYP4F2CYP4A11RIPK1
SCHEMBL5533824 0.83 MTNR1A (0.46) MTNR1AMTNR1BKDM4ECTSSCTSK
SCHEMBL21880654 0.83 MTNR1A (0.46) MTNR1AMTNR1BCYP4F2CYP4A11RIPK1
SCHEMBL2427540 0.83 MAPT (0.56) MTNR1AMTNR1BLMNA
SCHEMBL3135380 0.83 KMT2A (0.53) MTNR1AMTNR1BRIPK1RIPK3LMNA
SCHEMBL5866843 0.83 LOXL2 (0.46) MTNR1AMTNR1BKDM4ECYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739663-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-13 EP disclosed
US-20250214935-A1 METHOD FOR PRODUCING ARYL ESTER-CONTAINING CARBOXYLIC ACID AND METHOD FOR PRODUCING CATIONIC LIPID NOF CORPORATION (JP) 2025-07-03 US disclosed
US-20250127801-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2025-04-24 US disclosed
WO-2025080850-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-04-17 WO disclosed
EP-4506329-A1 METHOD FOR PRODUCING ARYL ESTER-CONTAINING CARBOXYLIC ACID AND METHOD FOR PRODUCING CATIONIC LIPID NOF Corporation (JP) 2025-02-12 EP disclosed
WO-2025008510-A1 IONIZABLE LIPIDS ETHERNA IMMUNOTHERAPIES NV (BE) 2025-01-09 WO disclosed
CN-118973994-A Method for producing carboxylic acid containing aryl ester and method for producing cationic lipid 日油株式会社 2024-11-15 CN disclosed
WO-2024203577-A1 CATIONIC LIPID HAVING DISULFIDE BOND 国立大学法人東北大学 2024-10-03 WO disclosed
US-11839659-B2 Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein NORTHWESTERN UNIVERSITY (US) 2023-12-12 US disclosed
WO-2023190164-A1 METHOD FOR PRODUCING ARYL ESTER-CONTAINING CARBOXYLIC ACID AND METHOD FOR PRODUCING CATIONIC LIPID 日油株式会社 2023-10-05 WO disclosed
CN-101119756-A Absorbent structure with improved water-absorbing material PROCTER & GAMBLE (US) 2008-02-06 CN disclosed
CN-1268618-C 1,5-benzothiazepines compounds and its use as antilipemic agent ASTRAZENECA AB (SE) 2006-08-09 CN disclosed
US-6974658-B2 HIGH MOLECULAR COMPOUND, MONOMER COMPOUNDS AND PHOTOSENSITIVE COMPOSITION FOR PHOTORESIST, PATTERN FORMING METHOD UTILIZING PHOTOSENSITIVE COMPOSITION, AND METHOD OF MANUFACTURING ELECTRONIC COMPONENTS KABUSHIKI KAISHA TOSHIBA (JP) 2005-12-13 US disclosed
CN-1481373-A 1,5-benzothiazepines compounds and its use as antilipemic agent 2004-03-10 CN disclosed
US-6207343-B1 RESIN CONTAINING GROUPS WHICH DECOMPOSE BY THE ACTION OF AN ACID TO ENHANCE ITS SOLUBILITY IN AN ALKALINE DEVELOPING SOLUTION AND A COMPOUND WHICH GENERATES AN ACID UPON IRRADIATION WITH ACTINIC RAYS OR RADIATION FUJI PHOTO FILM CO., LTD. (JP) 2001-03-27 US disclosed
US-5229381-A Inhibitors of leukocyte enzyme elastase MERCK & CO., INC. (US) 1993-07-20 US disclosed
EP-0481671-A1 New substituted azetidinones as anti-inflammatory and antidegenerative agents MERCK & CO. INC. (US) 1992-04-22 EP disclosed
EP-0048954-B1 BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-30 EP disclosed
US-4348410-A Cyclohexane carboxylic acid derivatives NIPPON CHEMIPHAR CO., LTD. (JP) 1982-09-07 US disclosed
EP-0048954-A2 Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1982-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839659-B2 Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein IDO1, IDO2, KMO CA2 4388/4885CAMK2A 1365/4885SENP1 224/4885
US-20250127801-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF SDHA, SDHB, DPYD CA2 2432/4885CAMK2A 3463/4885SENP1 577/4885
US-20250214935-A1 METHOD FOR PRODUCING ARYL ESTER-CONTAINING CARBOXYLIC ACID AND METHOD FOR PRODUCING CATIONIC LIPID LIPC, TSPO, CETP CA2 3142/4885CAMK2A 3879/4885SENP1 4375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.