Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336803 | 0.80 | CYP2C19 (0.48) | LMNASMN1; SMN2HTT | |
| SCHEMBL3072942 | 0.80 | TRPV1 (0.46) | LMNASMN1; SMN2HTT | |
| SCHEMBL2331598 | 0.80 | CYP2C19 (0.48) | LMNASMN1; SMN2HTT | |
| SCHEMBL9652157 | 0.79 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197364 | 0.79 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL15923360 | 0.79 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8909239 | 0.79 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31197375 | 0.79 | HTR1A (0.85) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL28014119 | 0.79 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL22966426 | 0.78 | LMNA (0.44) | HTR1AADRA1DADRA1AADRA1BS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067625-A1 | IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADASE ACTIVITY | WASHINGTON UNIVERSITY (US) | 2019-04-04 | — | — | WO | disclosed |