Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336803 | 1.00 | CYP2C19 (0.48) | CYP2C19NCF1HTTGALR3RAB9A | |
| SCHEMBL2331597 | 0.84 | CYP2C19 (0.49) | CYP2C19NCF1HTTGALR3RAB9A | |
| SCHEMBL20856477 | 0.80 | HTR1A (0.54) | HTTSMN1; SMN2LMNA | |
| SCHEMBL27895835 | 0.80 | CYP2C19 (0.66) | CYP2C19NCF1OPRK1 | |
| SCHEMBL28223102 | 0.80 | CYP2C19 (0.66) | CYP2C19NCF1OPRK1 | |
| SCHEMBL20856714 | 0.79 | CACNA2D1 (0.54) | RAB9AMEN1KMT2A | |
| Iodide SCHEMBL6297962 | 0.78 | CYP2C19 (0.64) | CYP2C19NCF1OPRK1 | |
| SCHEMBL19009075 | 0.75 | NR4A2 (0.59) | CYP2C19NCF1HTTGALR3RAB9A | |
| SCHEMBL16596179 | 0.74 | ALDH1A1 (0.71) | CYP2C19HTTGALR3RAB9ASMN1; SMN2 | |
| SCHEMBL15923206 | 0.73 | NCF1 (0.63) | CYP2C19NCF1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067625-A1 | IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADASE ACTIVITY | WASHINGTON UNIVERSITY (US) | 2019-04-04 | — | — | WO | disclosed |
| WO-2014140581-A1 | TRANSCRIPTION FACTOR DECOYS | PROCARTA BIOSYSTEMS LTD (GB) | 2014-09-18 | — | — | WO | disclosed |
| EP-2552455-A2 | TRANSCRIPTION FACTOR DECOYS | Procarta Biosystems Ltd (GB) | 2013-02-06 | — | — | EP | disclosed |
| EP-2533815-A1 | NUCLEIC ACID COMPLEXES | Procarta Biosystems Ltd (GB) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011121357-A2 | TRANSCRIPTION FACTOR DECOYS | PROCARTA BIOSYSTEMS LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011098829-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD (GB) | 2011-08-18 | — | — | WO | disclosed |