Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856584 | 0.90 | TGM2 (0.46) | TGM2PTPN1PTPN11TRPV1FGFR4 | |
| Alcohol SCHEMBL20856541 | 0.86 | THRA (0.43) | TGM2PTPN1PTPN11TRPV1ALDH1A1 | |
| SCHEMBL2386224 | 0.86 | ALDH1A1 (0.54) | TGM2PTPN1PTPN11TRPV1FGFR4 | |
| SCHEMBL20856368 | 0.85 | TGM2 (0.50) | TGM2PTPN1PTPN11FGFR4ALDH1A1 | |
| SCHEMBL9192222 | 0.84 | PTPN1 (0.47) | TGM2PTPN1PTPN11FGFR4ALDH1A1 | |
| SCHEMBL7178423 | 0.83 | EGFR (0.52) | TGM2ALDH1A1EGFRLMNA | |
| SCHEMBL10437098 | 0.83 | THRA (0.50) | TGM2PTPN1PTPN11EGFR | |
| SCHEMBL11409642 | 0.81 | TGM2 (0.44) | TGM2PTPN1PTPN11FGFR4ALDH1A1 | |
| SCHEMBL28738658 | 0.81 | THRA (0.56) | TGM2EGFR | |
| SCHEMBL15938830 | 0.81 | TGM2 (0.50) | TGM2PTPN1PTPN11FGFR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067396-A1 | ZAP-70 KINASE INHIBITOR COMPOSITIONS, METHODS AND USES THEREOF | SNAP BIO, INC. (US) | 2019-04-04 | — | — | WO | disclosed |