SCHEMBL20857028

SCHEMBL20857028

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)CCC(=O)O

nearest known ligand 0.92

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.84
▸ CHAT P28329 2/20 0.81
▸ EP300 Q09472 3/20 0.79
▸ KAT5 Q92993 2/20 0.79
▸ AURKA O14965 2/20 0.79
▸ KAT2B Q92831 1/20 0.79
▸ CREBBP Q92793 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218619 1.00 NAA50 (0.84) NAA50CHATEP300KAT5AURKA
Succinic Acid SCHEMBL29359560 1.00 NAA50 (0.84) NAA50CHATEP300KAT5AURKA
SCHEMBL285428 0.97 NAA50 (0.84) NAA50CHATEP300KAT5AURKA
SCHEMBL19181359 0.97 NAA50 (0.83) NAA50CHATEP300KAT5AURKA
SCHEMBL420710 0.96 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4360979 0.96 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL31385487 0.96 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4364428 0.96 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4360968 0.96 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL50744 0.96 NAA50 (0.87) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 — — CN claimed
CN-118922530-A Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or 3-oxo adipic acid and method for producing the same 东丽株式会社 2024-11-08 — — CN claimed
CN-118591634-A Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or alpha-hydrogenated hexadienoic acid and method for producing the same 东丽株式会社 2024-09-03 — — CN claimed
CN-111386339-B Genetically modified microorganisms for producing 3-hydroxy adipic acid, alpha-hydrogenated hexadienoic acid and/or adipic acid and method for producing the chemical products 东丽株式会社 2024-05-10 — — CN claimed
CN-116406420-A Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or alpha-hydrogenated hexadienoic acid and method for producing the same 东丽株式会社 2023-07-07 — — CN claimed
CN-116096869-A Engineered enzymes and methods of making and using the same 基因组股份公司 2023-05-09 — — CN claimed
CN-109154008-B Process for producing 3-hydroxyadipic acid 东丽株式会社 2022-05-31 — — CN claimed
CN-114144513-A Fermentative production of beta-ketoadipate from gaseous substrates 朗泽科技有限公司 2022-03-04 — — CN claimed
EP-3719121-A1 GENE-MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID, -HYDROMUCONIC ACID AND/OR ADIPIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS Toray Industries, Inc. (JP) 2020-10-07 — — EP claimed
CN-120082490-A Recombinant microorganism for producing adipic acid and hexamethylenediamine and application thereof 清华大学 2025-06-03 — — CN disclosed
CN-120077142-A Biological recycling of polyesters into PHAs 雀巢产品有限公司 2025-05-30 — — CN disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 — — CN disclosed
CN-118922530-A Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or 3-oxo adipic acid and method for producing the same 东丽株式会社 2024-11-08 — — CN disclosed
CN-118922530-A Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or 3-oxo adipic acid and method for producing the same 东丽株式会社 2024-11-08 — — CN disclosed
CN-113795589-A Genetically modified microorganisms for the production of 3-hydroxyadipic acid, alpha-hydrogenated adipic acid and/or adipic acid and methods for the production of such chemicals 东丽株式会社 2021-12-14 — — CN disclosed
CN-107636157-B Process for producing 3-hydroxyadipic acid 东丽株式会社 2021-10-26 — — CN disclosed
EP-3688169-A2 GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS Lanzatech, Inc. (US) 2020-08-05 — — EP disclosed
CN-111386339-A Genetically modified microorganism for producing 3-hydroxyadipic acid, α -hydrogenated adipic acid and/or adipic acid and method for producing chemical product 东丽株式会社 2020-07-07 — — CN disclosed
CN-111386339-A Genetically modified microorganism for producing 3-hydroxyadipic acid, α -hydrogenated adipic acid and/or adipic acid and method for producing chemical product 东丽株式会社 2020-07-07 — — CN disclosed
WO-2019068011-A2 GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS LANZATECH, INC. (US) 2019-04-04 — — WO disclosed
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