Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900976 | 0.81 | TTR (0.64) | NR1H3STK39RAF1TTRLPAR1 | |
| SCHEMBL12238995 | 0.81 | LOXL2 (0.46) | STK39RAF1TTRLPAR1LPAR5 | |
| SCHEMBL17653947 | 0.80 | ALDH1A1 (0.45) | RXRARXRBRXRGSMN1; SMN2 | |
| SCHEMBL27854362 | 0.76 | FFAR4 (0.46) | TTRCTNNB1SMN1; SMN2 | |
| SCHEMBL3320732 | 0.76 | RXRA (0.54) | NR1H3RXRARXRBRXRG | |
| SCHEMBL8059639 | 0.76 | TTR (0.62) | STK39RAF1TTRLPAR1LPAR5 | |
| Hydrochloric Acid SCHEMBL4027240 | 0.75 | RXRA (0.53) | NR1H3RXRARXRBRXRG | |
| SCHEMBL2734987 | 0.74 | SRD5A2 (0.62) | NR3C1SMN1; SMN2FFAR1 | |
| SCHEMBL1395777 | 0.73 | FFAR1 (0.56) | SMN1; SMN2FFAR1 | |
| SCHEMBL12984838 | 0.73 | NR3C2 (0.52) | NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688472-A1 | CONJUGATED PROTEINS AND USES THEREOF | The Scripps Research Institute (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019067741-A1 | CONJUGATED PROTEINS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-04-04 | — | — | WO | disclosed |