Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23553767 | 0.83 | KMT2A (0.60) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20468901 | 0.81 | DPP4 (0.43) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23553271 | 0.80 | HSD17B10 (0.45) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23553276 | 0.80 | DPP4 (0.48) | DPP4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL23185467 | 0.80 | EPHX2 (0.46) | ALDH1A1NPC1GAAEPHX2MAPT | |
| SCHEMBL30920935 | 0.79 | DPP4 (0.47) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2645027 | 0.79 | DPP4 (0.47) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16643863 | 0.78 | PTPN1 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL20381554 | 0.77 | CYP2D6 (0.50) | DPP4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL145918 | 0.77 | DPP4 (0.46) | DPP4MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246410-B2 | Hydrazinyl and aminooxy compounds and their methods of use | Life Technologies Corporation (US) | 2019-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246410-B2 | Hydrazinyl and aminooxy compounds and their methods of use | PHYKPL, AASDHPPT, CA14 | DPP4 127/4885MEN1 4112/4885KMT2A 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.