Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397880 | 0.94 | ERN1 (0.40) | ERN1CHRM2CHRM1CHRNB2CHRM3 | |
| SCHEMBL17397866 | 0.85 | LMNA (0.37) | ERN1MAPK1LMNAHPGDP2RX7 | |
| SCHEMBL25078221 | 0.82 | P2RX7 (0.35) | MAPK1P2RX7 | |
| SCHEMBL31394434 | 0.80 | MAPK1 (0.38) | MAPK1P2RX7 | |
| SCHEMBL17397902 | 0.80 | LMNA (0.47) | ERN1MAPK1LMNAHPGDDYRK1A | |
| SCHEMBL22802070 | 0.78 | LPL (0.33) | ERN1MAPK1P2RX7 | |
| SCHEMBL15056617 | 0.75 | MAPK1 (0.34) | ERN1MAPK1P2RX7 | |
| SCHEMBL20861650 | 0.74 | ERN1 (0.34) | ERN1 | |
| SCHEMBL552698 | 0.72 | ERN1 (0.32) | ERN1MAPK1P2RX7 | |
| SCHEMBL10158242 | 0.71 | MAPK1 (0.36) | MAPK1DYRK1ADYRK1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164404-B1 | TRICYCLIC BENZOXABOROLES AS ANTIBACTERIAL AGENTS | DAIICHI SANKYO CO LTD (JP) | 2019-04-03 | — | — | EP | disclosed |