SCHEMBL20865844 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	6/20	0.40

▸	ALDH1A1	P00352	6/20	0.40

▸	MEN1	O00255	2/20	0.40

▸	KMT2A	Q03164	2/20	0.40

▸	TDP1	Q9NUW8	4/20	0.38

▸	RECQL	P46063	1/20	0.36

▸	TSHR	P16473	4/20	0.35

▸	MAPT	P10636	3/20	0.35

▸	HTT	P42858	2/20	0.35

▸	NPC1	O15118	1/20	0.35

▸	MAPK1	P28482	1/20	0.33

▸	L3MBTL1	Q9Y468	1/20	0.33

▸	POLB	P06746	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	GAA	P10253	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6836629	0.76	L3MBTL1 (0.34)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL17170052	0.76	CA1 (0.35)	LMNAALDH1A1MEN1KMT2ARECQL
SCHEMBL15704785	0.74	COMT (0.34)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL6950212	0.74	ALDH1A1 (0.56)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL22284116	0.73	GAA (0.40)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL297761	0.73	ATM (0.40)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL19289811	0.73	P2RX7 (0.35)	LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL5780946	0.73	ALDH1A1 (0.45)	LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL21865974	0.72	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2ATDP1RECQL
SCHEMBL20810981	0.72	ALDH1A1 (0.48)	LMNAALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019062949-A1	COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF	上海海和药物研究开发有限公司	2019-04-04	—	—	WO	disclosed